Arthritis associated with Kawasaki disease after initial combination therapy with cyclosporine: a case report.

ABSTRACT:

Background

Since the 2020 revision of the Kawasaki disease (KD) treatment guidelines, there have been few reports of reactive arthritis secondary to treatment-resistant KD. This study reports a case of KD that required initial treatment with cyclosporine A (CyA) followed by additional infliximab (IFX) and secondary to reactive arthritis.

Case description

A 5-year-old boy met diagnostic criteria for KD on day 5 of fever and had an intravenous immunoglobulin (IVIG) refractory predictive score of 8 (≥5) was administered ulinastatin, IFX, and three IVIG doses in combination with CyA. His fever resolved on day 9. Subsequently, acetylsalicylic acid was changed to flurbiprofen and then to dipyridamole due to suspicion of a drug rash. Fever and pain appeared in ankle joints and righ

SUBMITTER: Yoshida K 

PROVIDER: S-EPMC12433033 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature