On-pump versus off-pump coronary artery bypass grafting for left main coronary artery disease: long-term outcomes.

ABSTRACT:

Background

Previous studies comparing off-pump versus on-pump coronary artery bypass grafting (CABG) have shown inconsistent results, especially for left main coronary artery disease (LM CAD), largely due to variations in surgical expertise. This study evaluates outcomes from a high-volume center with considerable experience in both techniques.

Methods

We retrospectively analyzed 1,410 patients with significant LM CAD (stenosis ≥70% or functionally significant 50-69%) who underwent isolated CABG between 2003 and 2017. The primary endpoint was a composite of death, myocardial infarction (MI), or stroke within 5 years. Analyses included Cox regression, inverse probability of treatment weighting (IPTW), and propensity score (PS) matching with adjustments for surgeon type and te

SUBMITTER: Kim TO 

PROVIDER: S-EPMC12433041 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature