Effect of aerobic exercise on the susceptibility of atrial fibrillation among aged mice.

ABSTRACT:

Background

Regular aerobic exercise has been shown to improve mitochondrial function and delay mitochondrial aging. Mitochondria play a crucial role in maintaining cardiac function and metabolism in myocardial cells. However, the effect of aerobic exercise on the incidence of atrial fibrillation (AF) is unclear. The aim of this study was to investigate the effects of aerobic exercise of different intensities on the susceptibility of aged mice to AF, and the relationship between altered mitochondrial structure and function and susceptibility to AF.

Methods

Thirty-two 18-month-old C57BL/6N aged mice were selected and divided into low-, medium-, and high-speed aerobic exercise groups, and a no-exercise control group. Electrophysiological characteristics, susceptibility to AF, m

SUBMITTER: Zhao C 

PROVIDER: S-EPMC12433064 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature