Outcomes and prognostic factors in primary intrathoracic soft tissue sarcoma.

ABSTRACT:

Background

Intrathoracic soft tissue sarcomas are rare and heterogenous tumors with limited data guiding their management. Due to anatomical complexity and delayed diagnosis, treatment can be challenging. This study aimed to assess clinical outcomes and prognostic factors in intrathoracic soft tissue sarcoma patients treated at a high-volume referral sarcoma center.

Methods

This bi-institutional retrospective cohort study (2007-2022) analyzed patients with histopathologically confirmed intrathoracic soft tissue sarcomas. Data from two prospective registries were used to assess overall survival (OS), local recurrence (LR), and distant metastasis (DM) via Kaplan-Meier, cumulative incidence, and multivariable Cox regression.

Results

Among 49 patients (median age: 56 year

SUBMITTER: Roohani S 

PROVIDER: S-EPMC12433095 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature