Monitoring human adenovirus loads in bronchoalveolar lavage fluid in non-immunocompromised children with human adenovirus pneumonia.

ABSTRACT:

Background

Human adenoviruses (HAdVs) are prevalent pathogens responsible for respiratory infections. In this study, we examined the relationship between adenovirus viral loads in bronchoalveolar lavage fluid (BALF) and the severity of adenovirus pneumonia in children.

Methods

The medical records of patients admitted to Guangzhou Women and Children's Medical Center with confirmed adenovirus pneumonia were analyzed in a prospective manner. We evaluated the potential link between the severity of the disease and the viral load, which was measured using real-time polymerase chain reaction (PCR) on the BALF of pediatric patients. Furthermore, the study investigated the connection between viral loads in BALF and the progression of the illness.

Results

In hospitalized pediat

SUBMITTER: Zeng S 

PROVIDER: S-EPMC12433097 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature