Estimates of Urinary Calcium Excretion in Dogs With and Without Calcium Oxalate Urolithiasis.

ABSTRACT:

Background

Fractional excretion of calcium (FeCa) and urine calcium-to-creatinine ratios (UCaCr) estimate hypercalciuria, but more data are needed on how well they discriminate between dogs with and without CaOx urolithiasis.

Objective

To determine the performance of FeCa and UCaCr in predicting CaOx urolith status.

Animals

One hundred twenty-one client-owned, normocalcemic dogs: 42 CaOx stone formers (cases) and 79 controls.

Methods

Analytical, retrospective, cross-sectional study. FeCa (%) and UCaCr (mg/mg) were calculated using measurements from urine and blood and were compared by urolith status with Wilcoxon rank-sum tests. Performance was determined with receiver operating characteristic curves; "optimal" thresholds were selected to maximize sensitivity a

SUBMITTER: LaVine DE 

PROVIDER: S-EPMC12433243 | biostudies-literature | 2025 Sep-Oct

REPOSITORIES: biostudies-literature