Prevalence of ocular and visual abnormalities following symptomatic and asymptomatic congenital CMV infection: a systematic review and meta-analysis.

ABSTRACT:

Background

Cytomegalovirus (CMV), the most common congenitally acquired infection, can result in visual disability in affected children. We aimed to estimate the burden of eye and vision disorders amongst children with symptomatic and asymptomatic congenital cytomegalovirus infection (cCMV), to inform the development of guidance for the provision of care.

Methods

In this systematic review and meta-analysis, we searched PubMed, Embase, and CINAHL databases up to 6th Feb 2025 for studies reporting ocular disorders or visual impairment (VI) outcomes following cCMV diagnosis. We included longitudinal or cross-sectional studies which reported the frequency of visual or ophthalmic outcomes following an initial diagnosis of symptomatic or asymptomatic cCMV. Summary data, and indivi

SUBMITTER: Schreiber T 

PROVIDER: S-EPMC12433491 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature