A mixed-effect model for the evolution of unbalanced longitudinal hematocrit levels in chronic kidney failure patients.

ABSTRACT:

Background

Chronic kidney disease, or renal failure, is a public health problem with an estimated prevalence of 8%-16% worldwide. This study was conducted to investigate the evolution of hematocrit levels over time in renal patients after transplantation and to determine how the evolution of hematocrit levels depends on the patients' age, sex, and other factors.

Objective

The main objective of this study was to employ a mixed-effects model to examine the unbalanced longitudinal evolution of hematocrit levels in chronic kidney failure patients.

Methodology

This longitudinal study included 1160 patients who received a renal transplant. These patients were followed for at most 10 years. The hematocrit level was considered the response, while the covariates were time in y

SUBMITTER: Fissuh YH 

PROVIDER: S-EPMC12433553 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature