Association between short-term glucose fluctuations and cognition in patients with acute ischemic stroke complicated by type 2 diabetes mellitus.

ABSTRACT:

Objectives

Glucose fluctuations are more harmful than persistent hyperglycemia for chronic complications of diabetes. However, the relationship between cognition and glucose fluctuations in patients with acute ischemic stroke (AIS) complicated by type 2 diabetes mellitus (T2DM) remains unclear. We aimed to evaluate the association between short-term glucose fluctuations and cognition in patients with AIS complicated by T2DM.

Design

A cohort study with a 2-year follow-up.

Setting and participants

We included 554 patients with mild AIS (mean age: 62 years; 170 females and 384 males).

Measurements

Glucose variability (GV) was evaluated using glycated hemoglobin (HbA1c), stress hyperglycemia (SHR), standard deviation of blood glucose (SDBG), mean postprandial blood

SUBMITTER: Zhou R 

PROVIDER: S-EPMC12433812 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature