Phytochemical and Bioactivity Profiling of Unconventional Food Plant, <i>Boehmeria caudata</i> Leaves: FT-IR, GC-MS, Experimental, and In Silico Investigation.

ABSTRACT: Boehmeria caudata (Urticaceae) is an unconventional food plant found extensively across the neotropical region, including Central and South America, where its leaves are consumed as vegetables and traditionally used to treat sore throats. This study aimed to analyze the phytochemical composition of the methanolic extract of B. caudata leaves (MEBCL) and explore its pharmacological effects through in vitro, in vivo, and in silico methods. GC-MS investigation identified 14 phytochemicals, including two forms of Vitamin E. MEBCL exhibited a strong in vitro antioxidant effect, with IC₅₀ values of 63.61 μg/mL for the DPPH assay as well as 130.66 μg/mL for the FRAP assay. In vivo, MEBCL showed notable analgesic effects, as observed in both the acetic

SUBMITTER: Ali ML 

PROVIDER: S-EPMC12433900 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature