Methodologies to detect cortico-cortical evoked potentials: a systematic review.

ABSTRACT:

Introduction

Cortico-cortical evoked potentials (CCEPs) are electrophysiological responses elicited by direct electrical stimulation of one cortical region and recorded from another, providing insights into functional connectivity and communication pathways between brain areas. However, no consistent standard for defining and measuring CCEPs currently exists.

Methods

We conducted a systematic review of the CCEP literature on detection methods to evaluate commonalities and gaps in methodology. Extracted data included demographics, disease, recording type, montage, recording system, stimulation amplitude and frequency, time window used for epoching around stimulus onset, open access availability, and detection approach.

Results

Of 187 studies undergoing full-text review

SUBMITTER: Al-Sadek T 

PROVIDER: S-EPMC12433984 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature