Assessing the association between the non-HDL to HDL cholesterol ratio and NAFLD in Chinese adults: concentrate on gout populations.

ABSTRACT:

Background

The coexistence and synergistic relationship between Nonalcoholic fatty liver disease (NAFLD) and gout necessitate an investigation into the risk factors for NAFLD among individuals with gout. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) serves as a comprehensive lipid index. This study aimed to investigate the association between NHHR and the risk of NAFLD in patients with gout.

Methods

A cross-sectional study was conducted involving 1,038 hospitalized patients with gout to examine the relationship between NHHR and NAFLD. NHHR was included in the logistic regression analysis as both a continuous and a categorical variable. Restricted cubic splines (RCS) were utilized to assess the dose-response relationship. Ad

SUBMITTER: Sun C 

PROVIDER: S-EPMC12433996 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature