Reward processing deficits: weakened self-reward association in individuals with methamphetamine addiction undergoing abstinence.

ABSTRACT: This research primarily investigates whether both reward processing and self-processing are aberrant in individuals with methamphetamine use disorder. It also explores whether initiating self-referential processing modulates reward processing abilities in this population, and how this modulation differs from that observed in healthy controls. Experiment 1 employed a two-factor mixed experimental design to compare the performance of addiction groups with varying withdrawal durations (all participants in the addiction groups were methamphetamine users) against healthy control groups in a probabilistic reward learning task. The results indicated that the healthy control group performed better than the addiction group in learning characters associated with high-probability, high-reward outcome

SUBMITTER: Yanghui X 

PROVIDER: S-EPMC12434089 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature