Risk factors for acute kidney injury in patients with acute pancreatitis and construction of nomogram model: a single-center study and external validation.

ABSTRACT:

Objective

This study aims to utilize clinical data from patients with acute pancreatitis (AP) recorded in the MIMIC-IV database to analyze the risk factors associated with acute kidney injury (AKI) and to develop a nomogram prediction model.

Methods

This study included clinical data from 754 patients diagnosed with AP sourced from the MIMIC-IV database. They were randomly divided into a training set and an internal validation set. Another 202 patients from the First Affiliated Hospital of Xi'an Jiaotong University were used as an external validation set. Univariate and multivariate logistic regression analyses were conducted to identify the independent influencing factors associated with AKI in these patients. A nomogram model was developed to predict the incidence of AKI, a

SUBMITTER: Chen F 

PROVIDER: S-EPMC12434119 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature