Longitudinal associations of carotid artery stiffness with progression of cerebrovascular disease, incident dementia and cognitive decline in older adults.

ABSTRACT:

Background

Carotid artery stiffness is associated with cerebrovascular disease (CeVD) and cognitive impairment, but evidence for its longitudinal effects on progression of CeVD and cognitive decline are limited.

Objectives

To evaluate the longitudinal associations of carotid artery stiffness with CeVD progression, incident dementia, and cognitive decline.

Design

Longitudinal analyses from a memory-clinic cohort with a follow-up of 2 years.

Setting

A memory-clinic study.

Participants

194 participants (mean age=80, 63 % female) with or without cognitive impairments provided consent to take part in the study.

Measurements

Participants underwent carotid ultrasonography, brain MRI, and neuropsychological assessments were at baseline and follow-up. Caro

SUBMITTER: Robert C 

PROVIDER: S-EPMC12434267 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature