Visual stimulus-evoked blood velocity responses in individual human posterior cerebral arteries measured with dynamic phase-contrast functional MR angiography.

ABSTRACT: Functional MRI (fMRI) tracks brain activity through the associated hemodynamic changes via neurovascular coupling. Neurons communicate with the microvessels of the parenchyma to initiate a hemodynamic response, and these microvessels then communicate with upstream arterioles and arteries. The role of the larger feeding arteries-far upstream from the site of neuronal activity-in coordinating this response is incompletely understood, yet is important for the interpretation of fMRI. Functional transcranial Doppler (fTCD) can noninvasively measure blood velocity changes in a subset of the largest macrovessels, albeit with poor spatial resolution, whereas existing functional MR angiography (fMRA) methods can assess blood velocity in mid-sized macrovessels but still lack the temporal resolution

SUBMITTER: Hu Z 

PROVIDER: S-EPMC12434382 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature