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The predictive value of cumulative plantar tissue stress on future plantar foot ulceration in people with diabetes-A 12-month prospective observational study.


ABSTRACT:

Aims

Plantar foot ulcers are a burdensome complication of diabetes caused by abnormal foot biomechanics. Predicting foot ulcers aids in their prevention, but the value of peak pressure-the most used biomechanical parameter-is only moderate. We aimed to improve prediction based on the more comprehensive load measure cumulative plantar tissue stress (CPTS).

Methods

We prospectively observed 60 participants with diabetes at high foot ulcer risk for 12 months. At baseline, we assessed demographic and clinical characteristics-including plantar pre-ulcers (i.e., abundant callus, haemorrhage, blister, fissure)-and measured barefoot and in-shoe plantar pressures during walking and standing. Daily-life weight-bearing activity and adherence to prescribed footwear were assessed over 7 

SUBMITTER: Hulshof CM 

PROVIDER: S-EPMC12434429 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature