Lung involvement in rheumatoid arthritis, a prospective study.

ABSTRACT:

Background

The prevalence of lung involvement in rheumatoid arthritis (RA) remains elusive. Therefore, we set up a multicentric prospective study to investigate the presence of interstitial lung disease (ILD), emphysema, bronchiolitis and nodules in early RA.

Methods

We recruited patients with RA and a disease duration from 1 to 10 years to screening. Patients underwent comprehensive respiratory evaluation consisting of an environmental questionnaire, high-resolution computed tomography (HRCT), pulmonary function tests (PFTs) and sampling for genetic analysis of common variants associated with RA-ILD. HRCT scans were centrally reviewed.

Results

We included 258 RA patients, median age 56 years old, 71% female and 49% ex- or current smokers. We detected ILD, emphysema a

SUBMITTER: Froidure A 

PROVIDER: S-EPMC12434487 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature