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ABSTRACT: Importance
Clinical practice guidelines advise balance training for cerebellar ataxia, but little is known regarding high-intensity aerobic exercise.Objective
To compare home high-intensity aerobic training to home balance training on improvements of ataxia symptoms using the Scale for the Assessment and Rating of Ataxia (SARA).Design, setting, and participants
This assessor-masked randomized clinical trial was conducted between January 1, 2021, and September 1, 2024, through home training, with in-person assessments at a single ataxia care center in a large urban US city. Individuals with various cerebellar ataxia types were eligible for inclusion. Data analysis was performed from November 2024 to February 2025.Interventions
Individuals in the aerobic group
SUBMITTER: Barbuto S
PROVIDER: S-EPMC12434599 | biostudies-literature | 2025 Nov
REPOSITORIES: biostudies-literature