Depressive Symptoms Profiles and Cognitive Outcomes After Stroke.

ABSTRACT:

Introduction

Post-stroke depressive symptoms are heterogeneous and variably associated with other psycho-cognitive features. We employed cluster analysis to identify distinct profiles of post-stroke depressive symptomatology and their association with cognitive performance.

Methods

We included consecutive patients undergoing neuropsychiatric evaluation 6 months after stroke. Cluster analysis incorporated the Center for Epidemiologic Studies Depression Scale, along with the apathy and anxiety items from the Neuropsychiatric Inventory questionnaire. Baseline clinical/neuroimaging variables and 6-months cognitive outcomes were compared across profiles.

Results

We included 189 patients with acute cerebrovascular events (median age 75.4 years, 62% male, 80% ischemic stroke

SUBMITTER: Scopelliti G 

PROVIDER: S-EPMC12434606 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature