Single-molecule graphene quantum dots: enhancement of optical properties and promotion of photodynamic efficacy based on precise control of the electronic structure.

ABSTRACT: Graphene quantum dots (GQDs) exhibit excellent optical properties, low toxicity, good biocompatibility, and high re-active oxygen species (ROS) generation efficiency under photoexcitation, demonstrating significant potential for achieving visualized therapy. However, conventional synthesis methods yield GQDs as multi-component mixtures with compromised safety and consistency, coupled with unclear luminescence mechanisms and difficulties in precise microstructure control, which severely hinder their development as nanomedicines. Therefore, it is urgent to synthesize mono-component single-molecule GQDs and systematically investigate the structure-property relationships governing their optical characteristics and ROS generation capabilities. This work established a modular organic synthetic s

SUBMITTER: Chen J 

PROVIDER: S-EPMC12434617 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature