Exploring magnetoelectric nanoparticles for advanced nano-electroporation and drug delivery in interventional cardiology.

ABSTRACT: Leveraging their ability to induce an intense and highly localized electric polarization upon application of an external magnetic field, core-shell magnetoelectric nanoparticles (MENPs) constitute powerful nanotools to achieve wireless nano-electroporation and targeted drug delivery in critical applications such as cardiovascular medicine, where frequent interventions may pose general yet high risks to the patients. In this study, the magnetoelectric feature is exploited to thoroughly map in silico the behavior of a model MENP under a set of either static or time-varying external magnetic fields, with the dual aim of (i) providing a series of operational parameters to elicit at the nanoscale a reversible cell membrane poration and (ii) correlating the electric potential difference d

SUBMITTER: Tommasini A 

PROVIDER: S-EPMC12434618 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature