Sex differences in life expectancy in dementia, mild cognitive impairment (MCI), and subjective cognitive decline (SCD).

ABSTRACT:

Introduction

It is unclear how dementia affects loss in life expectancy (LE). In this registry-based study, we aimed to study sex differences in LE and loss in LE in dementia, mild cognitive impairment (MCI), and subjective cognitive decline (SCD).

Methods

A total of 16,358 patients diagnosed with dementia, MCI, or SCD from the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) during 2009-2022 were included and followed up for mortality. Sex differences in LE and loss in LE were predicted using flexible parametric survival models and sex-specific mortality in the general population as reference.

Results

Among dementia patients, women with dementia had the largest loss in LE: 17 years loss at 60 years; correspondingly, men lost 13.5 years. Similar

SUBMITTER: Amland R 

PROVIDER: S-EPMC12434703 | biostudies-literature | 2025 Jul-Sep

REPOSITORIES: biostudies-literature