Association between heat and air pollution (PM_2.5 and black carbon) exposure in pregnancy and preterm birth in low- and middle-income countries: a systematic review and meta-analysis.

ABSTRACT:

Background

Preterm birth (PTB) is a major global health issue, causing substantial newborn morbidity and mortality. Limited literature is available on the association between prenatal exposure to heat and air pollution (particularly, particulate matter 2.5 (PM_2.5) and black carbon) and the risk of PTB in low- and middle-income countries (LMICs). This review attempts to integrate existing information.

Methods

A systematic search of numerous databases (Pubmed, Embase, Scopus and grey literature) for peer-reviewed articles published between 2010 and 2024 in LMIC was done using PM_2.5, black carbon and ambient heat as exposures with PTB as the outcome. After screening 4524 studies, 32 were included, focusing on various exposure windows throughout pregnancy.

SUBMITTER: Raghavan S 

PROVIDER: S-EPMC12434743 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature