Greater Central Adiposity Is Associated With Poorer Left Atrial Function: The Atherosclerosis Risk in Communities (ARIC) Study.

ABSTRACT:

Objective

To evaluate the association of longitudinal change in waist circumference (WC), waist-to-hip ratio (WHR), and body mass index (BMI) with left atrial (LA) function in the Atherosclerosis Risk in Communities study, a community-based cohort study.

Patients and methods

We included 4008 participants (mean age, 75.1 years; 59% female; 20% Black) with 2D speckle-tracking echocardiographic LA strain data and without prevalent heart failure or atrial fibrillation at visit (V)5. Measures of adiposity were obtained at V4 (1996-1998) and V5 (2011-2013). We categorized change in WC, BMI, or WHR from V4 to V5 as consistently low (reference group), consistently elevated, increasing, and decreasing. Multivariable linear regression was used to evaluate the association of change in

SUBMITTER: Reyes JL 

PROVIDER: S-EPMC12434983 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature