Real-world trends in rheumatic disease rates among pregnancies in Ontario, Canada: A repeated cross-sectional study.

ABSTRACT:

Objective

Despite increasing rheumatic disease prevalence among female individuals in Ontario, Canada, research is limited on whether this has translated to an increased proportion of pregnancies with rheumatic diseases. This study aimed to assess rheumatic disease rates among pregnant individuals in Ontario, Canada.

Methods

Using healthcare administrative claims databases from ICES, the proportion of pregnancies with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), psoriatic arthritis (PsA), and ankylosing spondylitis (AS) from April 2011 to March 2021 were examined. The Mann-Kendall rank correlation test was used to test for trends in overall and individual rheumatic disease rates across the study period.

Results

In total, 1,408,100 pregnancies were re

SUBMITTER: Tharmarajah S 

PROVIDER: S-EPMC12435662 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature