Phytochemical composition and bioactivities of Satureja montana L. and Satureja hortensis L.: Culinary herbs with antidiabetic, anticholinesterase, and antioxidant potential.

ABSTRACT: The increasing global burden of oxidative stress-related conditions, diabetes, and neurodegenerative disorders underscores the urgent need for multi-targeted, plant-based therapeutic agents. In this context, the present study aimed to evaluate the antidiabetic, antioxidant, and neuroprotective properties of various Satureja hortensis and Satureja montana extracts and essential oils. In vitro biological activities were assessed through α-glucosidase, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) inhibition assays, along with DPPH• and ABTS• ⁺ radical scavenging assays. At a concentration of 100 µg/mL, S. hortensis root methanol extract (ShRME) and herb water extract (ShHWE) exhibited strong α-glucosidase inhibitory activity (69.88% and 71.23%, respectively). Conversely, S. m

SUBMITTER: Coban F 

PROVIDER: S-EPMC12435695 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature