Isolation, characterization, and pathogenicity of a Vibrio parahaemolyticus strain causing translucent post-larvae disease in Penaeus vannamei outside China.

ABSTRACT: Translucent post-larvae disease (TPD) has emerged as a severe threat to shrimp aquaculture, causing substantial economic losses. The causative agent, Vibrio parahaemolyticus, has been primarily identified in China, but this study provides the first confirmed report of its presence in shrimp populations outside China. This research characterizes V. parahaemolyticus strain AG1 (VpTPD AG1), isolated from diseased Penaeus vannamei, through biochemical, molecular, and pathogenic analyses. PCR screening of VpTPD AG1 detected vhvp-1 and vhvp-2, genes previously linked to TPD virulence, while pirA/pirB genes associated with acute hepatopancreatic necrosis disease (AHPND) were absent. Experimental immersion challenges demonstrated high virulence and dose-dependent pathogenicity, with an LC50 of 8.5

SUBMITTER: Dinh-Hung N 

PROVIDER: S-EPMC12435696 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature