Risk prediction model for post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis.

ABSTRACT:

Background

Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common and clinically significant complication of ERCP, with an incidence of 3.5-9.7% in general populations and up to 14.7% in high-risk groups, leading to considerable morbidity, mortality, and healthcare costs. Although numerous multivariable prediction models have been developed, their predictor sets, methodological rigor, and clinical applicability remain highly variable.

Method

We conducted a PRISMA 2020-compliant systematic review and meta-analysis, prospectively registered in PROSPERO (CRD42024556967). Nine databases were searched to June 1, 2024, for studies developing or validating multivariable PEP risk prediction models. Data on study/model characteristics, predictors, a

SUBMITTER: Mao Y 

PROVIDER: S-EPMC12435719 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature