Optimizing resistance training for pain management in knee and hip osteoarthritis: a pairwise and dose-response meta-analysis.

ABSTRACT:

Background

Osteoarthritis (OA) is a degenerative joint disease affecting approximately 300 million people worldwide. OA manifests as significant pain and stiffness as well as reduced mobility, substantially impacting patient quality of life and imposing considerable financial burdens on healthcare systems. Although resistance training (RT) demonstrates therapeutic potential, existing studies vary widely in its intensity, duration, and effectiveness, necessitating comprehensive dose-response analyses.

Objective

This study aimed to evaluate the effectiveness of RT interventions in the management of OA pain.

Methods

A systematic literature search was performed of the PubMed/MEDLINE, Embase, Cochrane Library, and Web of Science databases. Effect sizes were computed using

SUBMITTER: Liu W 

PROVIDER: S-EPMC12436098 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature