Secular trend of gestational diabetes mellitus and its interaction effect with advanced maternal age on adverse maternal-perinatal outcomes among primiparous singleton and twin pregnancies in Hubei, China (2011-2019).

ABSTRACT:

Background

Gestational diabetes mellitus (GDM) is a metabolic disorder of pregnancy associated with multiple adverse maternal-perinatal outcomes among singleton and twin pregnancies and its incidence is increasing across the globe. We aimed to find the secular trend of GDM and its interaction effect with advanced maternal age (AMA) on adverse maternal-perinatal outcomes among primiparous singleton and twin pregnancies in Hubei, China.

Methods

A retrospective-based cohort study was conducted at the Wuhan University Renmin Hospital, Hubei Province, China, between 2011 and 2019. A chi-square test was used to explore a significant difference in the adverse maternal-perinatal outcomes between younger (18-34 years) and older/AMA (≥35 years) women with singleton and twin gestations

SUBMITTER: Nawsherwan 

PROVIDER: S-EPMC12436103 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature