Determinants of orphan drug health technology assessment in South Korea: an empirical analysis.

ABSTRACT:

Background

Orphan drug pricing in South Korea, including its workings and determinants, is a complicated aspect of the country's healthcare system. Therefore, this study identified the factors associated with the pricing of orphan drugs in South Korea.

Methods

The study screened 66 orphan drugs out of the whole set of newly reimbursed drugs from 2012 to 2022. The analysis presented the characteristics of the orphan drugs and accounted for correlations between treatment cost and other seemingly related variables. Formal multivariate regression analysis indicated associated factors in multivariate settings.

Results

Annual treatment cost per patient displayed a weakly negative correlation with the number of patients. Meanwhile, treatment cost exhibited a strongly positiv

SUBMITTER: Lee SH 

PROVIDER: S-EPMC12436107 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature