ANKK1 Taq1A Gene Variance and Executive Functions in Female Youth with Binge Eating Disorder: A Cross-sectional Study.

ABSTRACT:

Background

Binge eating disorder (BED) biological and psychological etiology is still not fully understood. This study investigates the relationship between the ANKK1 Taq1A gene variant and BED in female youth with obesity, while also assessing executive functions (EFs).

Methods

The study included eighty young females with obesity, divided into BED and non-BED groups. EFs were assessed using the Stroop test, Digit Span, and the PEBL battery (including Card Sorting, Iowa Gambling, and Go/No-go tests). The ANKK1 Taq1A gene variance was detected via real-time PCR.

Results

No significant differences were found in ANKK1 Taq1A genotypes or allele frequencies between the groups. However, the BED group exhibited worse cognitive flexibility, decision-making, and higher depress

SUBMITTER: Ibrahim OM 

PROVIDER: S-EPMC12436327 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature