Case Report: A large granular cell tumor of the cervical esophagus with single cell RNA sequencing analysis.

ABSTRACT: Esophageal granular cell tumor (GCT) is a rare benign neurogenic tumor, however, malignant transformation has been reported. And there is no consensus on the choice of esophageal reconstruction in these patients. Therefore, the study of markers of malignant potential in GCT is of great importance in guiding the choice of clinical treatment. Case presentation: Herein, we report the case of a patient with a large cervical esophageal GCT in which a myocutaneous free flap was used to repair a large defect after the resection of a localized esophageal tumor, providing strong reliability in terms of coverage capacity, tissue resistance, and distance management from the recipient vessel. The patient's recovery was satisfactory at 48 days postoperatively, without significant complications. To furt

SUBMITTER: Shao C 

PROVIDER: S-EPMC12436342 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature