Feasibility of pulsed field ablation for atrial fibrillation under mild conscious sedation.

ABSTRACT:

Background

Pulsed field ablation (PFA) is a new modality for pulmonary vein isolation (PVI) for atrial fibrillation (AF). PFA is performed under general anaesthetic (GA) or deep sedation with propofol, but this requires anaesthetic support in many countries, restricting use. No study has tested the feasibility of PFA under mild conscious sedation (MCS).

Methods

We prospectively recruited patients undergoing PFA PVI, offered the option of MCS delivered by electrophysiologists, and compared these with patients who opted for GA. MCS comprised intravenous midazolam and fentanyl. All procedures were performed under anaesthetic supervision in case of requirement to convert to GA, which formed the primary outcome.

Results

Twenty-three patients were recruited (8 MCS, 15 GA).

SUBMITTER: Calvert P 

PROVIDER: S-EPMC12436502 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature