Longitudinal functional and neuropsychological 2-year follow-up after intensive care admission for multisystem inflammatory syndrome in children.

ABSTRACT: The purpose of this study is to investigate long-term morbidity (physical, psychosocial, neurocognitive, quality of life (QoL)) in critical care patients with multisystem inflammatory syndrome in children (MIS-C). This prospective study examined MIS-C critical care admissions (May 2020-March 2022). Outcomes were determined by semi-structured interview, functional assessment scores, self- and parent-reported questionnaires, and extensive neurocognitive testing at 3 and 24 months after pediatric intensive care unit (PICU) admission. There was no control group, but general population norm data was used. Thirty-six MIS-C PICU admissions were included (median [IQR] age 10.1 [7.9-13.6] years, 72% male). Median [IQR] PICU stay was 3 days [2-4] and all survived; 81% (29/36) attended 24 months foll

SUBMITTER: Ketharanathan N 

PROVIDER: S-EPMC12436537 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature