Clinical Testing for COVID-19, Influenza, and RSV in Hospitalized Youths, 2016-2024.

ABSTRACT:

Importance

Studies of COVID-19, influenza, and respiratory syncytial virus (RSV) disease clinical epidemiology, disease burden, and vaccine effectiveness often rely on clinical testing to identify cases, particularly with increasing use of electronic health record data. However, few data are available describing clinical testing practices to inform interpretation of these studies.

Objective

To characterize clinical testing frequency for SARS-CoV-2, influenza, and RSV among children and adolescents hospitalized with acute respiratory illness during the 2016 to 2024 respiratory illness seasons by age, intensive care unit admission, and time period (2016-2020 and each season in 2020-2024); estimate the case fraction missed by clinical testing alone; and identify patient charact

SUBMITTER: Toepfer AP 

PROVIDER: S-EPMC12439058 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature