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Ultrasound-assisted extraction of phenolic compounds from walnut (Juglans regia L.) shell waste using choline chloride-based natural deep eutectic solvents (NADES): an in vitro bioaccessibility study.


ABSTRACT:

Background

Walnut shells, which are discarded as waste at both household and industrial levels, are good sources of phenolic compounds. The aim of this study was to apply an ultrasound-assisted extraction method using ten different choline chloride (ChCl)-based natural deep eutectic solvents (NADES) to recover phenolic compounds from walnut shell waste (WSW) and to evaluate the in vitro bioaccessibility of the resulting green extracts. The phenolic compounds were identified and quantified using ultra-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Results

The results revealed that quercitrin and taxifolin were the predominant flavonoids in WSW, while ellagic acid was the dominant phenolic acid. Bioaccessible total phenolic con

SUBMITTER: Erdem A 

PROVIDER: S-EPMC12439087 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature