Paratyphoid fever and the genomics of Salmonella enterica serovar Paratyphi A in Taiwan.

ABSTRACT:

Background

Salmonella enterica serovar Paratyphi A (S. Paratyphi A) has emerged as a significant global health concern due to the progressive development of antimicrobial resistance and its broader geographic distribution. In Taiwan, paratyphoid fever was historically rare and predominantly associated with imported cases. Since 2022, however, a marked increase in domestically acquired infections has been observed, prompting investigations into their origin and likely route of introduction.

Methods

We analyzed surveillance data on 223 patients with paratyphoid fever reported in Taiwan between January 2001 and December 2024. Whole-genome sequencing and antimicrobial susceptibility testing were performed on 88 S. Paratyphi A isolates obtained from both imported and domestically

SUBMITTER: Liao YS 

PROVIDER: S-EPMC12440159 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature