Prevalence and Risk Factors of Depression in Patients With Endemic Osteoarthritis Kashin-Beck Disease.

ABSTRACT: Background: Kashin-Beck disease (KBD) is an endemic osteoarthropathy, which occurs in children aged 3-12, with similarity to osteoarthritis (OA). Previous studies have shown significant depression symptoms in OA patients, yet no comparable research has been conducted in KBD patients. Methods: We conducted a field investigation in KBD areas in Northwest China. Questionnaires were designed and used to assess demographic characteristics, clinical characteristics, and medical comorbidities. Patient Health Questionnaire-9 (PHQ-9) was included for the prevalence of depression. Finally, 440 subjects were clinically diagnosed and recruited. Depression was diagnosed when PHQ-9 ≥ 5 and classified into mild (5-9), moderate (10-14), and severe (≥ 15) groups. Logistic regression was also

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12440642 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature