MR radiomics in assessment of consistency of pituitary macroadenoma: can T1-weighted contrast enhanced image improve diagnostic performance of T2-weighted image?

ABSTRACT:

Objectives

To evaluate and compare the efficacy of radiomics models derived from T2-weighted and/or contrast-enhanced T1-weighted (CET1) images in assessing pituitary macroadenoma consistency, and to validate their performance stability under varying MRI field strengths and scanner vendors.

Methods

A total of 133 patients with pathologically proven pituitary macroadenomas (35 fibrous, 98 non-fibrous) were retrospectively included. Three logistic regression models were constructed: a T2 model, a CET1 model, and a T2-CET1 combined model, based on features selected from coronal T2-weighted and contrast-enhanced T1-weighted (CET1) images. An external validation cohort of 40 patients (20 fibrous, 20 non-fibrous) was selected from another healthcare institutio

SUBMITTER: Zou M 

PROVIDER: S-EPMC12440780 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature