Global burden of inflammatory bowel disease in children and adolescents, 1990-2021: trends, age-specific patterns and future projections.

ABSTRACT:

Introduction

Recent epidemiological trends have revealed a marked increase in incidence among children and adolescents. This study aimed to analyze the global burden of inflammatory bowel disease (IBD) among children and adolescents aged 0-19 years from 1990 to 2021 systematically, focusing on regional and age-specific trends and future projections, with the aim of informing global prevention and control strategies.

Methods

Data on IBD incidence, mortality, and disability-adjusted life years (DALYs) were obtained for 204 countries and territories from the Global Burden of Disease Study 2021 (GBD 2021). Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). A Bayesian age-period-cohort (BAPC) model was use

SUBMITTER: Tan HQ 

PROVIDER: S-EPMC12440882 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature