Diagnostic Accuracy of 24-Hour Urinary Aldosterone for Primary Aldosteronism in Northeast China.

ABSTRACT: This study aimed to evaluate the diagnostic accuracy of 24-hour urinary aldosterone (UALD) for primary aldosteronism (PA) in Northeast China. A total of 423 patients with hypertension were consecutively enrolled. After 1:2 propensity score matching (PSM), 100 patients were classified into the PA group, and 194 patients were classified into the essential hypertension (EH) group. The clinical characteristics and biochemistry measurements were collected and analyzed. A receiver operating characteristic (ROC) curve was generated, and the area under the curve (AUC) was calculated to determine optimal diagnostic thresholds. No significant difference in age was observed between the groups (PA: 53.4 ± 11.3 years vs. EH: 52.8 ± 11.3 years, p > 0.05). The median 24-hour UALD was significantly greate

SUBMITTER: Sun K 

PROVIDER: S-EPMC12441307 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature