Treating Concomitant Advanced Heart Failure and Advanced Cancer With Left Ventricular Assist Device, Surgery, and Biologics.

ABSTRACT: The diagnosis of cancer in the context of evaluation for advanced heart failure therapies represents a psychosocial and therapeutic challenge. We present a case report of a patient with breast cancer diagnosed during heart transplantation evaluation. A 63-year-old female presented with anterior ST-segment elevation myocardial infarction and severe left ventricular dysfunction 2 months prior. She was readmitted because of heart failure decompensation and diagnosed with inotrope-dependent stage D heart failure. Routine pre-heart transplantation evaluation diagnosed Stage IIIb breast cancer. She underwent left ventricular assist device (LVAD) implantation, neoadjuvant chemo-immunotherapy, mastectomy, adjuvant radiation, and adjuvant immunotherapy. Three years after LVAD implantation, she is a

SUBMITTER: Campbell B 

PROVIDER: S-EPMC12441378 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature