Delayed Diagnoses of Cardiac Amyloidosis.

ABSTRACT: Cardiac sarcoidosis (CS) can be challenging to accurately diagnose and relies on a complex diagnostic framework because of the limited sensitivity of endomyocardial biopsy. Frequently, the diagnosis of CS depends on cardiac ¹⁸F-fluorodeoxyglucose positron emission tomography, which has limited specificity for sarcoidosis. We report 3 cases of individuals who were initially diagnosed and treated for isolated CS based on multimodality cardiac imaging and later definitively reclassified to wild-type transthyretin cardiac amyloidosis from histopathology obtained by endomyocardial biopsy.

SUBMITTER: Kersey CB 

PROVIDER: S-EPMC12441432 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature