Kratom-Associated Acute Right Ventricular Dysfunction: Diagnostic and Management Insights.

ABSTRACT:

Background

Kratom (Mitragyna speciosa) is a psychoactive herbal supplement with stimulant and opioid-like properties, with emerging reports linking it to cardiovascular toxicity. However, its association with right ventricular (RV) function remains unclear.

Case summary

We report the case of a 52-year-old man who presented in shock with hypoxia and multiorgan dysfunction. Echocardiography revealed severe RV dilation with McConnell's sign, whereas chest computed tomography angiography ruled out pulmonary embolism. Right heart catheterization confirmed elevated right-sided pressures and high cardiac output consistent with high-output RV failure.

Discussion

Despite intermittent Kratom use, other etiologies, including thyrotoxicosis, arteriovenous fistula, liver disease,

SUBMITTER: Alameh I 

PROVIDER: S-EPMC12441496 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature