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ABSTRACT: Background
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare vasculitis; cardiac involvement is common and worsens prognosis.Case summary
A 42-year-old man presented with chest pain, marked ST-T changes, eosinophilia, and elevated troponin, without obstructive coronary disease. He was diagnosed with acute eosinophilic endomyocarditis, mildly reduced left ventricular (LV) ejection fraction, and a large apical thrombus-an initial manifestation of probable EGPA. The patient received anticoagulation, corticosteroids, and immunosuppressive therapy. Endomyocardial fibrosis was confirmed via LV biopsy. During follow-up, electrocardiography and troponin T normalized, cardiac magnetic resonance (CMR) showed thrombus resolution, LV function recovery, and persistent suben
SUBMITTER: Pereyra Acha E
PROVIDER: S-EPMC12441530 | biostudies-literature | 2025 Jul
REPOSITORIES: biostudies-literature