Transcatheter Aortic Valve Replacement and Percutaneous Coronary Intervention After Ozaki Procedure in Alagille Syndrome.

ABSTRACT:

Background

The Ozaki procedure is a novel therapeutic alternative to aortic valve replacement that involves excision of the native valve and replacement with neo-leaflets trimmed from the patient's pericardium.

Case summary

A 35-year-old man with Alagille syndrome and severe symptomatic stenosis of his neo-aortic valve was admitted 4 years after an Ozaki procedure. Given his high risk of redo surgery and nonsusceptibility to oral anticoagulation, valve-in-valve transcatheter aortic valve replacement (TAVR) with RESILIA tissue was performed. Despite preoperative imaging and good feasibility of TAVR after Ozaki, temporary obstruction of the right coronary artery occurred after TAVR, which was successfully resolved by ostial stent implantation.

Discussion

Published repor

SUBMITTER: Mayr B 

PROVIDER: S-EPMC12441554 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature