Biomimetic Enamel-like Crystals: A Versatile Platform for Unraveling the Basic Mechanisms of Demineralization and Remineralization.

ABSTRACT: Enamel is a cellular, nonregenerative, highly mineralized tissue essential for the mechanical durability and wear resistance of human teeth. Combating its degradation necessitates effective remineralization strategies, with hydroxyapatite (HAp) playing a central role in both natural and synthetic enamel restoration. Fluoride incorporation enhances HAp stability, forming fluoridated hydroxyapatite (FHAp), which is widely used to prevent or resist dental caries and improve remineralization. However, a mechanistic understanding of demineralization and remineralization remains incomplete due to the limitations of conventional ex situ techniques, which fail to capture real-time crystal dissolution and growth dynamics. In this study, we developed and applied a facile synthesis method for oriente

SUBMITTER: Chang J 

PROVIDER: S-EPMC12442002 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature