B(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub>-Catalyzed Coupling of <i>N</i>-Alkyl Arylamines and Alkenes for the Synthesis of Tetrahydroquinolines.
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ABSTRACT: Tetrahydroquinolines are featured in molecules with wide ranging properties, including those with biological activity and materials applications. This report demonstrates that widely accessible N-alkyl arylamines can be directly coupled with new classes of alkenes to synthesize tetrahydroquinolines. The reaction is facilitated by a commercially available borane catalyst and enables the creation of novel tetrahydroquinoline scaffolds.
SUBMITTER: Gloria SM
PROVIDER: S-EPMC12442061 | biostudies-literature | 2025 Sep
REPOSITORIES: biostudies-literature
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